Nucleic acid extraction and purification is an important aspect of genetic testing since it supplies the starting material for any genetic study, and significant advances have been made in establishing techniques to offer high-quality nucleic acid for future genetic research. 

The emergence of modern technology with automated systems and ways to acquire high-quality nucleic acid has facilitated the extraction, isolation, purification, and other processes in sample preparation. Increased demand for high-quality reagent kits and related items has resulted from advancements in the nucleic acid sample preparation procedure. Various researchers and manufacturers have developed automated resources to generate high-quality samples in quick turnaround periods. High throughput and sophisticated sample preparation technology, as well as collaborations developed with key research institutions throughout the world to improve sampling methodology, are expected to fuel market expansion during the forecast period 2022-2032.

Nucleic Acid Sample Preparation Market is projected to reach $11,200.5 million by 2032 from $4,213.0 million in 2022, growing at a CAGR of 10.27% during the forecast period 2022-2032. The growth in the global nucleic acid sample preparation market is expected to be driven by the increased use of nucleic acid molecules in several therapeutic areas. In addition, the increased demand for downstream applications such as next-generation sequencing (NGS) and others and the advancement in nucleic acid extraction/isolation techniques have driven the growth of the nucleic acid sample preparation market.

Market Lifecycle Stage

The global nucleic acid sample preparation market is in a progressing phase. To meet the growing need for timely diagnostic information and targeted patient treatment, several molecular procedures, including automated nucleic acid sample preparation workstations, have been developed. In addition, sample preparation is essential in precision medicine because it assures the safe and successful use of tailored therapies. The market offers a range of universal products with varied maximum throughputs, innovations, time durations, and other qualities, and companies are searching for innovative methods to distinguish themselves. Additionally, manufacturers began to produce application-specific nucleic acid purification devices and liquid handlers in recent years.

Market Segmentation:

Segmentation 1: by Product

•    Systems

•    Consumables

•    Accessories and Components

Based on product, the consumables segment in the global nucleic acid sample preparation market dominated in FY2021. This was due to the increase in the adoption of kits and reagents in this market.

Segmentation 2: by Workflow

•    Sample Extraction/Isolation

•    Sample Quantification

•    Quality Control

•    Fragmentation

•    Target Enrichment

•    Library Quantification

•    Pooling

Based on the workflow, the global nucleic acid sample preparation market was dominated by sample extraction/isolation in FY2021. The high share associated with sample extraction/isolation in the nucleic acid sample preparation ecosystem is majorly attributed to the growing prevalence of oncology medical conditions and rising emphasis on research procedures.

Segmentation 3: by Technology

•    Spin-Column Based Technology

•    Magnetic-Bead Based Technology

•    Other Technologies

Based on technology, the spin column-based technology segment accounted for the largest share of the global nucleic acid sample preparation in FY2021. The large share of this segment can be attributed to the increasing adoption of global nucleic acid sample preparation products, the growing demand to perform rapid and efficient extraction, and the rising need to reduce the sample-to-sample variation arising from the manual process.

Segmentation 4: by Therapeutic Area

•    Oncology

•    Human Genetics/Population Genetics

•    Infectious Disease

•    Others

Based on the therapeutic area, the global nucleic acid sample preparation market was dominated by the oncology segment in FY2021, owing to an increase in cancer cases. Sample preparation can make a big difference in the field of oncology because it offers a number of benefits in terms of sensitivity, specificity, and outcomes.

Segmentation 5: by Application

•    Genomics

•    Proteomics

•    Other Applications

Based on application, the global nucleic acid sample preparation market was dominated by the genomics segment in FY2021. The term next-generation sequencing (NGS) refers to novel DNA sequencing methods that offer high speed and throughput and may generate a large number of sequences with a wide range of potential uses in research and diagnostic contexts.

Segmentation 6: by End User

•    Academic and Research Institutions

•    Pharmaceutical and Biotechnology Companies

•    Clinical and Diagnostic Laboratories

•    Other End Users

As of 2021, the global nucleic acid sample preparation market (by end user) was dominated by academic and research institutions. Academic institutions' contributions to the nucleic acid sample preparation market are quite advantageous. Variable kits and instruments are typically employed in research settings to evaluate possible medical and diagnostic uses.

Segmentation 7: by Region

•    North America

•    Europe

•    Asia Pacific

•    Latin America

•    Rest-of-the-World

In 2021, the North America nucleic acid sample preparation market dominated the global market with a 46.99% market share, and it is expected to hold its dominance throughout the forecast period 2022-2032. However, the Asia-Pacific (APAC) region, constituting several emerging economies, is expected to register the highest CAGR of 12.01% during the forecast period 2022-2032.

Impact of COVID-19

In December 2019, Wuhan, a city in the Hubei region of China, was the site of the first detection of the COVID-19 outbreak. Following the classification of COVID-19 as novel pneumonia due to a cluster of unexplained pneumonia cases, efforts to pinpoint the culprit causing the outbreak and outline its genomic sequence got underway right once. The virus has already spread to every country on the globe, and researchers, governments, and business leaders are working to find answers to the crisis at a scale and speed that has never been seen. Testing for SARS-CoV-2 in the populace is one of the main steps that has been put into place globally, among many other measures used to stop the spread of the disease. The most crucial benefit of testing is that it offers evidence of illness, enabling individuals and those they have come into contact with to take the required precautions, including quarantining, to minimize community exposure.

Key Companies Profiled

•    Agilent Technologies, Inc.
•    Aurora Biomed Inc.
•    BGI Group (MGI Tech Co., Ltd.)
•    BIONEER CORPORATION.
•    Blue-Ray Biotech Corp.
•    Danaher. (Beckman Coulter, Inc.)
•    Endress+Hauser Group Services AG (Analytik Jena GmbH)
•    Eppendorf SE
•    F. Hoffmann-La Roche Ltd
•    Illumina, Inc.
•    Merck KGaA
•    Norgen Biotek Corp.
•    OPENTRONS
•    PerkinElmer Inc.
•    Promega Corporation
•    QIAGEN
•    Sansure Biotech Inc.
•    Tecan Trading AG
•    Thermo Fisher Scientific Inc.

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Key Questions Answered in the Report

▪ How is the nucleic acid sample preparation market revolutionizing the nucleic acid sample preparation instruments and kits ? 

▪ What are the major market drivers, restraints, and opportunities in the global nucleic acid sample preparation market? 

▪ What are the underlying structures resulting in the emerging trends within the nucleic acid sample preparation market? 

▪ How did the COVID-19 pandemic impact the global nucleic acid sample preparation market? ▪ What are the key development strategies that are being implemented by major players to sustain themselves in the market? 

▪ What are the key regulatory implications in developed and developing regions pertaining to the use of nucleic acid sample preparation market?

▪ What are the potential entry barriers that are expected to be faced by the companies willing to enter a particular region in the market? 

▪ What will be the growth rate of the global nucleic acid sample preparation market during the forecast period 2022-2032? 

▪ How is each segment of the market expected to grow during the forecast period 2022-2032, and what revenue is anticipated to be generated by each of the segments? The following are the segments: o Product (Consumables, Systems, and Accessories and Components) o Workflow (Sample Extraction/Isolation, Sample Quantification, Quality control (QC), Fragmentation, Target Enrichment, and Pooling

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