Tadalista 10 mg is a medication used for the treatment of erectile dysfunction (ED) in men. It contains the active ingredient tadalafil, which is a phosphodiesterase type 5 (PDE5) inhibitor. Tadalafil works by increasing blood flow to the penis during sexual stimulation, facilitating the ability to achieve and maintain an erection. Tadalafil inhibits the action of PDE5, an enzyme that breaks down cyclic guanosine monophosphate (cGMP) in the smooth muscle cells of the penis. Increased levels of cGMP result in smooth muscle relaxation, leading to improved blood flow and the facilitation of an erection.